Research Projects

Hope Against Cancer’s focus is to beat cancer rather than manage the consequences. Here you can find out about the vital research projects that we fund for the early detection, treatment and prevention of cancer.

LIQUID BIOPSY

Liquid biopsies as a method of early detection of relapse in colorectal cancer

Awarded: £150,000

Serial Monitoring of Circulating Tumour DNA for Early Detection of Recurrence.

Awarded to: Dr Alessandro Rufini

Starting 1st September 2017

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PRECISION MEDICINES

Precision medicines in the treatment of lymphoma and leukaemia

Awarded: £100,000

Precision medicines in the treatment of lymphoma and leukaemia.

Awarded to: Departments of Molecular and Cell Biology and Cancer Studies - University of Leicester

Starting May 2017

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BOWEL (COLORECTAL) CANCER

Can curcumin benefit patients with bowel cancer?

Awarded: £90,000

Does taking daily doses of curcumin in combination with chemotherapy, benefit patients with bowel cancer?

Researcher: Dr Chinenye Iwuji

January 2012 - December 2014

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BOWEL (COLORECTAL) CANCER

The use of curcumin as a cancer prevention agent in bowel cancer

Awarded: £150,000

Curcumin may be used as prevention agent and in the treatment of in bowel cancer.

Awarded to: Department of Cancer Studies

Researcher: Dr Sameena Khan MBChB MRes MRCP(UK)

Leicester Centre of Excellence - January 2015 - 2017

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EARLY DETECTION

The use of cell free DNA as a liquid biopsy

Awarded: £150,000

The use of cell free DNA as a liquid biopsy.

Awarded to: Department of Cancer Studies

Researcher: Dr Mark Openshaw MBChB MA(Oxon) MRCP(UK)

Leicester Centre of Excellence - January 2015 - 2017

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CANCER RESEARCH

Investigation into inhibitors that promote cancer cell death

Awarded: £5,000

Experiments on specific inhibitors of mitosis which can promote cancer cell death. This work may lead to a clinical trial.

Awarded to: Department of Biochemistry at the University of Leicester

Leicester Centre of Excellence - January 2013 - 2017

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CANCER RESEARCH

Small molecule kinase inhibitor library

Awarded: £9,300

A resource for developing new cancer drugs.

Awarded to: Department of Cancer Studies and Molecular Medicine and Biochemistry at the University of Leicester

Leicester Centre of Excellence - January 2015

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Predicting how patients react to radiotherapy

Awarded: £6,990

Evaluation of predictive tests to enable more targeted and patient specific treatment.

Awarded to: Department Cancer Studies and Molecular Medicine and MRC Toxicology at the University of Leicester

Leicester Centre of Excellence - January 2015

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LYMPHOMA

Testing a potential drug for use in T-cell lymphomas

Awarded: £9,000

Impact of antibodies on lymphoma.

Awarded to: Department Cancer Studies and Molecular Medicine at the University of Leicester

Leicester Centre of Excellence - January 2015

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LUNG CANCER

The role of the protein PRDM6 in thoracic cancer and lymphoma

Awarded: £5,000

The role of the protein PRDM6 in thoracic cancer and lymphoma.

Awarded to: Department of Biochemistry and Cancer at Studies and Molecular Medicine at the University of Leicester

Leicester Centre of Excellence - January 2015

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IMPROVING THE CANCER JOURNEY FOR LGBT PEOPLE

Improving the cancer journey for lesbian, gay and bisexual people living with cancer

Awarded: £16,400

An investigation into the quality of life, support and experiences of LGBT with cancer.

Awarded to: Department of Social Sciences at De Montfort University

June 2014

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CONSULTATION

Improving patient care with a consultation support tool

Awarded: £18,600

The development of a Consultation Support Tool for communication between doctors and patients will improve the consultation experience for patients.

Awarded to: University of Leicester Hospitals NHS Trust

June 2014

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HODGKIN’S LYMPHOMA

Development of a blood or urine test to improve treatments for Hodgkin's Lymphoma.

Awarded: £35,000

Development of a blood or urine test to improve treatments for Hodgkin's Lymphoma.

Awarded to: De Montfort University's School of Pharmacy

May 2014

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LEUKAEMIA

Development of an approach to cause the death of cancer cells in the blood

Awarded: £40,000

Development of an approach to cause the death of cancer cells in the blood.

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PANCREATIC CANCER

Using blood tests to identify pancreatic cancer

Awarded: £75,000

Investigation to see if pancreatic cancer can be detected earlier by looking at the mutations of circulating free DNA in the blood.

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